Just over a year ago, three physician-scientists were honored with the 2016 Albert Lasker Basic Medical Research Award for their discovery of the pathway by which cells from human and most animals sense and adapt to changes in oxygen availability, a process that is essential for survival. As referenced on the Albert and Mary Lasker Foundation website, scientists had long appreciated that the success of today’s dominant life forms hinges on oxygen, yet little was known about their responses to it. One of the recipients in particular, Peter J. Ratcliffe, has conducted his research related to oxygen sensing, first using simple incubators, then in 1999 by using the first InvivO2 400 workstations. The InvivO2 400 was developed by Ruskinn in collaboration with Professors Peter Ratcliffe, Chris Pugh and Jacques Pouyssegur. Since 1999, Professor Sir Peter Ratcliffe and Professor Chris Pugh, have written a multitude of hypoxia related publications powered by their work inside the Baker Ruskinn InvivO2 400 Workstations. Watch the short, 6 min. video produced by the Albert and Mary Lasker Foundation highlighting their discovery, and see the InvivO2 in action!
Need references for your physiological or anaerobic study? Browse this extensive list of more than 900 articles using key words and other easy-to-search criteria. These articles represent more than 15 years of research in hypoxia and anoxia, with many entries linking directly to abstracts for your further investigation.