Prof Giovanni Mann, King’s College London
This project will measure the levels, distribution and movement of metals under different oxygen levels within coronary artery cells. In the future, this could help in the diagnosis and treatment of coronary heart disease. Using a special oxygen-controlled workstation (Baker Ruskinn), Professor Mann and the team will carry out experiments with cells grown in the lab under different oxygen levels to mimic healthy hearts, as well as CHD and reperfusion. They will measure the levels and distribution of metals, focusing on zinc, and map them to different regions in coronary artery cells. If successful, the findings may help in the diagnosis and treatment of CHD in the future.
Find out more on the Heart Reserach UK website!