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Transportable system enabling multiple irradiation studies under simultaneous hypoxia in vitro


Cells in solid tumours are variably hypoxic and hence resistant to radiotherapy - the essential role of oxygen in the efficiency of irradiation has been acknowledged for decades. However, the currently available methods for performing hypoxic experiments in vitro have several limitations, such as a limited amount of parallel experiments, incapability of keeping stable growth conditions and dependence on CO2 incubator or a hypoxia workstation.

The purpose of this study was to evaluate the usability of a novel portable system (OxyGenie™ a.k.a. Minihypoxy) in performing in vitro irradiation studies under hypoxia, and present supporting biological data.

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