Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12.
Antonio Rodriguez-Sinovas, Jose A. Sanchez, Alejandra Gonzalez-Loyola, Ignasi Barba, Miriam Morente, Rio Aguilar, Esperanza Agulla, Elisatet Mira-Casas, Neus Esquerda, Marisol Ruiz-Meana, and David Garcia-Dorado
Constitutive/Hypoxic Degradation of HIF-α Proteins by the Proteasome Is Independent of von Hippel Lindau Protein Ubiquitylation and the Transactivation Activity of the Protein*