United Kingdom (Oxford) Archives

Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability

1 February 2010

Isabel M. Pires, Zuzana Bencokova, Manuela Milani, Lisa K. Folkes, Ji-Liang Li, Mike R. Stratford, Adrian L. Harris, and Ester M. Hammond

Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling

1 August 2009

By Nevena Djuranovic

Naseer Qayum, Ruth J. Muschel, Jae Hong Im, Lukxmi Balathasan, Cameron J. Koch, Sonal Patel, W. Gillies McKenna, and Eric J. Bernhard

hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer

1 March 2008

By Nevena Djuranovic

Carme Camps, Francesca M. Buffa, Stefano Colella, John Moore, Christos Sotiriou, Helen Sheldon, Adrian L. Harris, Jonathan M. Gleadle, and Jiannis Ragoussis

Genetic Analysis of the Role of the Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-inducible Factor (HIF) in Regulating HIF Transcriptional Target Genes

1 October 2004

By Nevena Djuranovic

Ineke P. Stolze, Ya-Min Tian, Rebecca J. Appelhoff, Helen Turley, Charles C. Wykoff, Jonathan M. Gleadle, and Peter J. Ratcliffe

Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor

1 September 2004

By Nevena Djuranovic

Rebecca J. Appelhoff, Ya-Min Tian, Raju R. Raval, Helen Turley, Adrian L. Harris, Christopher W. Pugh, Peter J. Ratcliffe, and Jonathan M. Gleadle

Anoxic induction of ATF-4 through HIF-1–independent pathways of protein stabilization in human cancer cells

1 March 2004

By Nevena Djuranovic

Kurosh Ameri, Claire E. Lewis, Martin Raida, Heidi Sowter, Tsonwin Hai, and Adrian L. Harris

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

1 October 2001

By Nevena Djuranovic

Andrew C.R. Epstein, Jonathan M. Gleadle, Luke A. McNeill, Kirsty S. Hewitson, John O’Rourke, David R. Mole, Mridul Mukherji, Eric Metzen, Michael I. Wilson, Anu Dhanda, Ya-Min Tian, Norma Masson, Donald L. Hamilton, Panu Jaakkola, Robert Barstead, Jonathan Hodgkin, Patrick H. Maxwell, Christopher W. Pugh, Christopher J. Schofield, and Peter J. Ratcliffe

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain

1 July 2001

By Nevena Djuranovic

Emma C. Vaux, Eric Metzen, Kay M. Yeates, and Peter J. Ratcliffe

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O₂-Regulated Prolyl Hydroxylation

1 April 2001

By Nevena Djuranovic

Panu Jaakkola, David R. Mole, Ya-Min Tian, Michael I. Wilson, Janine Gielbert, Simon J. Gaskell, Alexander von Kriegsheim, Holger F. Hebestreit, Mridul Mukherji, Christopher J. Schofield, Patrick H. Maxwell, Christopher W. Pugh, and Peter J. Ratcliffe

Applications

Solutions

United Kingdom (Oxford)

Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability

Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling

hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer

Genetic Analysis of the Role of the Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-inducible Factor (HIF) in Regulating HIF Transcriptional Target Genes

Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor

Anoxic induction of ATF-4 through HIF-1–independent pathways of protein stabilization in human cancer cells

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O₂-Regulated Prolyl Hydroxylation

Applications

Solutions

United Kingdom (Oxford)

Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability

Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling

hsa-miR-210 Is Induced by Hypoxia and Is an Independent Prognostic Factor in Breast Cancer

Genetic Analysis of the Role of the Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-inducible Factor (HIF) in Regulating HIF Transcriptional Target Genes

Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor

Anoxic induction of ATF-4 through HIF-1–independent pathways of protein stabilization in human cancer cells

C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O₂-Regulated Prolyl Hydroxylation