Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular disease
Read more about Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular diseaseKirsten Brukamp, Belinda Jim, Marcus J. Moeller, and Volker H. Haase
United States (Philadelphia)
HIF2α inhibition promotes p53 pathway activity, tumor cell death, and radiation responses
Read more about HIF2α inhibition promotes p53 pathway activity, tumor cell death, and radiation responsesJessica A. Bertout, Amar J. Majmundar, John D. Gordan, Jennifer C. Lam, Dara Ditsworth, Brian Keith, Eric J. Brown, Katherine L. Nathanson, and M. Celeste Simon
Erythrocytosis-associated HIF-2α Mutations Demonstrate a Critical Role for Residues C-terminal to the Hydroxylacceptor Proline
Read more about Erythrocytosis-associated HIF-2α Mutations Demonstrate a Critical Role for Residues C-terminal to the Hydroxylacceptor ProlinePaul W. Furlow, Melanie J. Percy, Scott Sutherland, Charlene Bierl, Mary Frances McMullin, Stephen R. Master, Terence R. J. Lappin, and Frank S. Lee
Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress Pathways
Read more about Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress PathwaysDiane R. Fels, Jiangbin Ye, Andrew T. Segan, Steven J. Kridel, Michael Spiotto, Michael Olson, Albert C. Koong, and Constantinos Koumenis
Hypoxic Reactive Oxygen Species Regulate the Integrated Stress Response and Cell Survival
Read more about Hypoxic Reactive Oxygen Species Regulate the Integrated Stress Response and Cell SurvivalLiping Liu, David R. Wise, J. Alan Diehl, and M. Celeste Simon
Hypoxia-mediated Selective mRNA Translation by an Internal Ribosome Entry Site-independent Mechanism
Read more about Hypoxia-mediated Selective mRNA Translation by an Internal Ribosome Entry Site-independent MechanismRegina M. Young, Shang-Jui Wang, John D. Gordan, Xinjun Ji, Stephen A. Liebhaber, and M. Celeste Simon
A Gain-of-Function Mutation in the HIF2A Gene in Familial Erythrocytosis
Read more about A Gain-of-Function Mutation in the HIF2A Gene in Familial ErythrocytosisMelanie J. Percy, Paul W. Furlow, Guy S. Lucas, Xiping Li, Terence R.J. Lappin, Mary Frances McMullin, and Frank S. Lee
Normoxic stabilization of HIF-1α drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk
Read more about Normoxic stabilization of HIF-1α drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral diskAmit Agrawal, Asha Guttapalli, Srinivas Narayan, Todd J. Albert, Irving M. Shapiro, and Makarand V. Risbud
The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
Read more about The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysisJulian J. Lum, Thi Bui, Michaela Gruber, John D. Gordan, Ralph J. DeBerardinis, Kelly L. Covello, M. Celeste Simon, and Craig B. Thompson
Multiple Factors Affecting Cellular Redox Status and Energy Metabolism Modulate Hypoxia-Inducible Factor Prolyl Hydroxylase Activity In Vivo and In Vitro
Read more about Multiple Factors Affecting Cellular Redox Status and Energy Metabolism Modulate Hypoxia-Inducible Factor Prolyl Hydroxylase Activity In Vivo and In VitroYi Pan, Kyle D. Mansfield, Cara C. Bertozzi, Viktoriya Rudenko, Denise A. Chan, Amato J. Giaccia, and M. Celeste Simon