The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 is Essential for Efficient Hydroxylation of Hypoxia Inducible Factor-α.
1 June 2016
By
Nevena Djuranovic
Read more about The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 is Essential for Efficient Hydroxylation of Hypoxia Inducible Factor-α.
Arsenault PR, Song D, Chung YJ, Khurana TS, Lee FS
PIM kinase inhibitors kill hypoxic tumor cells by reducing Nrf2 signaling and increasing reactive oxygen species.
1 May 2016
By
Nevena Djuranovic
Read more about PIM kinase inhibitors kill hypoxic tumor cells by reducing Nrf2 signaling and increasing reactive oxygen species.
Warfel NA, Sainz AG, Song JH, Kraft AS
Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health.
1 April 2016
By
Nevena Djuranovic
Read more about Circadian factors BMAL1 and RORα control HIF-1α transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health.
Suyama K, Silagi ES, Choi H, Sakabe K, Mochida J, Shapiro IM, Risbud MV
Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models.
1 April 2016
By
Nevena Djuranovic
Read more about Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models.
Benito J, Ramirez MS, Millward NZ, Velez J, Harutyunyan KG, Lu H, Shi YX, Matre P, Jacamo R, Ma H, Konoplev S, McQueen T, Volgin A, Protopopova M, Mu H, Lee J, Bhattacharya PK, Marszalek JR, Davis RE, Bankson JA, Cortes JE, Hart CP, Andreeff M, Konopleva M
A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germlinehaploinsufficiency of SART1/HAF in mice.
1 March 2016
By
Nevena Djuranovic
Read more about A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germlinehaploinsufficiency of SART1/HAF in mice.
Koh MY, Gagea M, Sargis T, Lemos R Jr, Grandjean G, Charbono A, Bekiaris V, Sedy J, Kiriakova G, Liu X, Roberts LR, Ware C, Powis G
Differential regulation of LncRNA-SARCC suppresses VHL-mutant RCC cell proliferation yet promotes VHL-normal RCC cell proliferation via modulating androgen receptor/HIF-2α/C-MYC axis under hypoxia.
1 March 2016
By
Nevena Djuranovic
Read more about Differential regulation of LncRNA-SARCC suppresses VHL-mutant RCC cell proliferation yet promotes VHL-normal RCC cell proliferation via modulating androgen receptor/HIF-2α/C-MYC axis under hypoxia.
Zhai W, Sun Y, Jiang M, Wang M, Gasiewicz TA, Zheng J, Chang C
Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation.
1 February 2016
By
Nevena Djuranovic
Read more about Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation.
Park YH, Broyles HV, He S, McGrady NR, Li L, Yorio T
Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth.
1 February 2016
By
Nevena Djuranovic
Read more about Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth.
Nakazawa MS, Eisinger-Mathason TS, Sadri N, Ochocki JD, Gade TP, Amin RK, Simon MC
Class I and IIa HDACs Mediate HIF-1α Stability through PHD2-Dependent Mechanism while HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc
3 January 2016
By
Nevena Djuranovic
Read more about Class I and IIa HDACs Mediate HIF-1α Stability through PHD2-Dependent Mechanism while HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc
Schoepflin ZR, Shapiro IM, Risbud M
WNT16-expressing Acute Lymphoblastic Leukemia Cells are Sensitive to Autophagy Inhibitors after ER Stress Induction
1 September 2015
By
Nevena Djuranovic
Read more about WNT16-expressing Acute Lymphoblastic Leukemia Cells are Sensitive to Autophagy Inhibitors after ER Stress Induction
Verras M, Papandreou I, Denko NC