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Overcoming Hypoxia-Induced Apoptotic Resistance through Combinatorial Inhibition of GSK-3β and CDK1

1 August 2011

By Nevena Djuranovic

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Patrick A. Mayes, Nathan G. Dolloff, Colin J. Daniel, J. Judy Liu, Lori S. Hart, Kageaki Kuribayashi, Joshua E. Allen, David I.H. Jee, Jay F. Dorsey, Yingqiu Y. Liu, David T. Dicker, J. Martin Brown, Emma E. Furth, Peter S. Klein, Rosalie C. Sears, and Wafik S. El-Deiry

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

1 July 2011

By Nevena Djuranovic

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Nora Grahl, Srisombat Puttikamonkul, Jeffrey M. Macdonald, Michael P. Gamcsik, Lisa Y. Ngo, Tobias M. Hohl, Robert A. Cramer

Impaired response of mature adipocytes of diabetic mice to hypoxia.

1 July 2011

By Nevena Djuranovic

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Hong SJ, Jin da P, Buck DW 2nd, Galiano RD, Mustoe TA.

Hypoxic regulation of β-1,3-glucuronyltransferase 1 expression in nucleus pulposus cells of the rat intervertebral disc: role of hypoxia-inducible factor proteins

1 July 2011

By Nevena Djuranovic

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Gogate SS, Nasser R, Shapiro IM, Risbud MV.

The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion

1 June 2011

By Nevena Djuranovic

Read more about The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion

Mei Yee Koh, Robert Lemos, Jr, Xiuping Liu, and Garth Powis

Differential Hypoxic Regulation of Hypoxia-Inducible Factors 1α and 2α

1 June 2011

By Nevena Djuranovic

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Qun Lin, Xiangyu Cong, and Zhong Yun

Intracoronary mesenchymal stem cells promote postischemic myocardial functional recovery, decrease inflammation, and reduce apoptosis via a signal transducer and activator of transcription 3 mechanism

1 May 2011

By Nevena Djuranovic

Read more about Intracoronary mesenchymal stem cells promote postischemic myocardial functional recovery, decrease inflammation, and reduce apoptosis via a signal transducer and activator of transcription 3 mechanism

Poynter JA, Herrmann JL, Manukyan MC, Wang Y, Abarbanell AM, Weil BR, Brewster BD, Meldrum DR.

5′-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.

1 May 2011

By Nevena Djuranovic

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Jang T, Calaoagan JM, Kwon E, Samuelsson S, Recht L, Laderoute KR.

Apigenin down-regulates the hypoxia response genes: HIF-1α, GLUT-1, and VEGF in human pancreatic cancer cells.

1 May 2011

By Nevena Djuranovic

Read more about Apigenin down-regulates the hypoxia response genes: HIF-1α, GLUT-1, and VEGF in human pancreatic cancer cells.

Melstrom LG, Salabat MR, Ding XZ, Strouch MJ, Grippo PJ, Mirzoeva S, Pelling JC, Bentrem DJ.

Hypoxia increases transepithelial electrical conductance and reduces occludin at the plasma membrane in alveolar epithelial cells via PKC- and PP2A pathway

1 April 2011

By Nevena Djuranovic

Read more about Hypoxia increases transepithelial electrical conductance and reduces occludin at the plasma membrane in alveolar epithelial cells via PKC- and PP2A pathway

Juan Carlos Caraballo, Cecilia Yshii, Maria L. Butti, Whitney Westphal, Jennifer A. Borcherding, Chantal Allamargot, and Alejandro P. Comellas